Endogenous CCN family member WISP1 inhibits trauma-induced heterotopic ossification

Heterotopic ossification (HO) is defined as abnormal differentiation of local stromal cells of mesenchymal origin, resulting in pathologic cartilage and bone matrix deposition. Cyr61, CTGF, Nov (CCN) family members are matricellular proteins that have diverse regulatory functions on cell proliferati...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hsu, Ginny Ching-Yun, Marini, Simone, Negri, Stefano, Wang, Yiyun, Xu, Jiajia, Pagani, Chase, Hwang, Charles, Stepien, David, Meyers, Carolyn A., Miller, Sarah, McCarthy, Edward, Lyons, Karen M., Levi, Benjamin, James, Aaron W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406255/
https://ncbi.nlm.nih.gov/pubmed/32484792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135432
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