Endogenous CCN family member WISP1 inhibits trauma-induced heterotopic ossification

Heterotopic ossification (HO) is defined as abnormal differentiation of local stromal cells of mesenchymal origin, resulting in pathologic cartilage and bone matrix deposition. Cyr61, CTGF, Nov (CCN) family members are matricellular proteins that have diverse regulatory functions on cell proliferati...

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Gepubliceerd in:JCI Insight
Hoofdauteurs: Hsu, Ginny Ching-Yun, Marini, Simone, Negri, Stefano, Wang, Yiyun, Xu, Jiajia, Pagani, Chase, Hwang, Charles, Stepien, David, Meyers, Carolyn A., Miller, Sarah, McCarthy, Edward, Lyons, Karen M., Levi, Benjamin, James, Aaron W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406255/
https://ncbi.nlm.nih.gov/pubmed/32484792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135432
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