Treatment Potential for LCA5-Associated Leber Congenital Amaurosis

PURPOSE: To determine the therapeutic window for gene augmentation for Leber congenital amaurosis (LCA) associated with mutations in LCA5. METHODS: Five patients (ages 6–31) with LCA and biallelic LCA5 mutations underwent an ophthalmic examination including optical coherence tomography (SD-OCT), ful...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Uyhazi, Katherine E., Aravand, Puya, Bell, Brent A., Wei, Zhangyong, Leo, Lanfranco, Serrano, Leona W., Pearson, Denise J., Shpylchak, Ivan, Pham, Jennifer, Vasireddy, Vidyullatha, Bennett, Jean, Aleman, Tomas S.
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2020
Предметы:
Retina
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405811/
https://ncbi.nlm.nih.gov/pubmed/32428231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.5.30
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы