CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival

Durable humoral immunity against epidemic infectious disease requires the survival of long-lived plasma cells (LLPCs). LLPC longevity is dependent on metabolic programs distinct from short-lived plasma cells (SLPCs); however, the mechanistic basis for this difference is unclear. We have previously s...

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Vydáno v:Cell Rep
Hlavní autoři: Utley, Adam, Chavel, Colin, Lightman, Shivana, Holling, G. Aaron, Cooper, James, Peng, Peng, Liu, Wensheng, Barwick, Benjamin G., Gavile, Catherine M., Maguire, Orla, Murray-Dupuis, Megan, Rozanski, Cheryl, Jordan, Martha S., Kambayashi, Taku, Olejniczak, Scott H., Boise, Lawrence H., Lee, Kelvin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405645/
https://ncbi.nlm.nih.gov/pubmed/32579940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107815
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