Dopamine 2 Receptor Signaling Controls the Daily Burst in Phagocytic Activity in the Mouse Retinal Pigment Epithelium

PURPOSE: A burst in phagocytosis of spent photoreceptor outer fragments by RPE is a rhythmic process occurring 1 to 2 hours after the onset of light. This phenomenon is considered crucial for the health of the photoreceptors and RPE. We have recently reported that dopamine, via dopamine 2 receptor (...

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Bibliografiske detaljer
Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Goyal, Varunika, DeVera, Christopher, Laurent, Virginie, Sellers, Jana, Chrenek, Micah A., Hicks, David, Baba, Kenkichi, Iuvone, P. Michael, Tosini, Gianluca
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2020
Fag:
Retinal Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7405625/
https://ncbi.nlm.nih.gov/pubmed/32396631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.5.10
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