Removal of clock gene Bmal1 from the retina affects retinal development and accelerates cone photoreceptor degeneration during aging

The mammalian retina contains an autonomous circadian clock system that controls many physiological functions within this tissue. Previous studies on young mice have reported that removal of the key circadian clock gene Bmal1 from the retina affects the circadian regulation of visual function, but d...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Baba, Kenkichi, Piano, Ilaria, Lyuboslavsky, Polina, Chrenek, Micah A., Sellers, Jana T., Zhang, Shuo, Gargini, Claudia, He, Li, Tosini, Gianluca, Iuvone, P. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305005/
https://ncbi.nlm.nih.gov/pubmed/30498030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808137115
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