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Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via the formation of non-bilayer, immobiliz...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Li, Feng, Shrivastava, Indira H., Hanlon, Paul, Dagda, Ruben K., Gasanoff, Edward S.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404710/
https://ncbi.nlm.nih.gov/pubmed/32605112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12070425
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