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Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via the formation of non-bilayer, immobiliz...

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Bibliographic Details
Published in:Toxins (Basel)
Main Authors: Li, Feng, Shrivastava, Indira H., Hanlon, Paul, Dagda, Ruben K., Gasanoff, Edward S.
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404710/
https://ncbi.nlm.nih.gov/pubmed/32605112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12070425
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