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Electrophysiological Alterations of Pyramidal Cells and Interneurons of the CA1 Region of the Hippocampus in a Novel Mouse Model of Dravet Syndrome

Dravet syndrome is a developmental epileptic encephalopathy caused by pathogenic variation in SCN1A. To characterize the pathogenic substitution (p.H939R) of a local individual with Dravet syndrome, fibroblast cells from the individual were reprogrammed to pluripotent stem cells and differentiated i...

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Bibliografski detalji
Izdano u:Genetics
Glavni autori: Dyment, David A., Schock, Sarah C., Deloughery, Kristen, Tran, Minh Hieu, Ure, Kerstin, Nutter, Lauryl M. J., Creighton, Amie, Yuan, Julie, Banderali, Umberto, Comas, Tanya, Baumann, Ewa, Jezierski, Anna, Boycott, Kym M., Mackenzie, Alex E., Martina, Marzia
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404236/
https://ncbi.nlm.nih.gov/pubmed/32554600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.120.303399
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