Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability

Nuclear β-dystroglycan (β-DG) is involved in the maintenance of nuclear architecture and function. Nonetheless, its relevance in defined nuclear processes remains to be determined. In this study we generated a C2C12 cell-based DG-null model using CRISPR-Cas9 technology to provide insights into the r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Jimenez-Gutierrez, Guadalupe Elizabeth, Mondragon-Gonzalez, Ricardo, Soto-Ponce, Luz Adriana, Gómez-Monsiváis, Wendy Lilián, García-Aguirre, Ian, Pacheco-Rivera, Ruth Abigail, Suárez-Sánchez, Rocío, Brancaccio, Andrea, Magaña, Jonathan Javier, C.R. Perlingeiro, Rita, Cisneros, Bulmaro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404207/
https://ncbi.nlm.nih.gov/pubmed/32674290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21144961
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker