Resolvin D1 and D2 Inhibit Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Ion Channel Activation on Sensory Neurons via Lipid Raft Modification

Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons and regulate nociceptor and inflammatory functions. Resolvins are endogenous lipid mediators. Resolvin D1 (RvD1) is described as a selective inhibitor of TRPA1-r...

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Udgivet i:Int J Mol Sci
Main Authors: Payrits, Maja, Horváth, Ádám, Biró-Sütő, Tünde, Erostyák, János, Makkai, Géza, Sághy, Éva, Pohóczky, Krisztina, Kecskés, Angéla, Kecskés, Miklós, Szolcsányi, János, Helyes, Zsuzsanna, Szőke, Éva
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404206/
https://ncbi.nlm.nih.gov/pubmed/32708653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145019
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