Loss of miR-145-5p Causes Ceruloplasmin Interference with PHD-Iron Axis and HIF-2α Stabilization in Lung Adenocarcinoma-Mediated Angiogenesis

For decades, lung cancer has been the leading cause of cancer-related death worldwide. Hypoxia-inducible factors (HIFs) play critical roles in mediating lung cancer development and metastasis. The present study aims to clarify how HIF’s over-activation affects lung cancer angiogenesis not only in a...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Tsai, Ying-Ming, Wu, Kuan-Li, Chang, Yung-Yun, Chang, Wei-An, Huang, Yung-Chi, Jian, Shu-Fang, Tsai, Pei-Hsun, Lin, Yi-Shiuan, Chong, Inn-Wen, Hung, Jen-Yu, Hsu, Ya-Ling
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7404111/
https://ncbi.nlm.nih.gov/pubmed/32708433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21145081
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