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TCF20 dysfunction leads to cortical neurogenesis defects and autistic‐like behaviors in mice

Recently, de novo mutations of transcription factor 20 (TCF20) were found in patients with autism by large‐scale exome sequencing. However, how TCF20 modulates brain development and whether its dysfunction causes ASD remain unclear. Here, we show that TCF20 deficits impair neurogenesis in mouse. TCF...

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Bibliografische gegevens
Gepubliceerd in:EMBO Rep
Hoofdauteurs: Feng, Chao, Zhao, Jinyue, Ji, Fen, Su, Libo, Chen, Yihui, Jiao, Jianwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403713/
https://ncbi.nlm.nih.gov/pubmed/32510763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949239
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