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TCF20 dysfunction leads to cortical neurogenesis defects and autistic‐like behaviors in mice

Recently, de novo mutations of transcription factor 20 (TCF20) were found in patients with autism by large‐scale exome sequencing. However, how TCF20 modulates brain development and whether its dysfunction causes ASD remain unclear. Here, we show that TCF20 deficits impair neurogenesis in mouse. TCF...

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Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Feng, Chao, Zhao, Jinyue, Ji, Fen, Su, Libo, Chen, Yihui, Jiao, Jianwei
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403713/
https://ncbi.nlm.nih.gov/pubmed/32510763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201949239
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