CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction

At the neuromuscular junction (NMJ), lipoprotein‐related receptor 4 (LRP4) mediates agrin‐induced MuSK phosphorylation that leads to clustering of acetylcholine receptors (AChRs) in the postsynaptic region of the skeletal muscle. Additionally, the ectodomain of LRP4 is necessary for differentiation...

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Vydáno v:EMBO Rep
Hlavní autoři: Ohkawara, Bisei, Kobayakawa, Akinori, Kanbara, Shunsuke, Hattori, Takako, Kubota, Satoshi, Ito, Mikako, Masuda, Akio, Takigawa, Masaharu, Lyons, Karen M, Ishiguro, Naoki, Ohno, Kinji
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403661/
https://ncbi.nlm.nih.gov/pubmed/32558157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948462
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