CTGF/CCN2 facilitates LRP4‐mediated formation of the embryonic neuromuscular junction

At the neuromuscular junction (NMJ), lipoprotein‐related receptor 4 (LRP4) mediates agrin‐induced MuSK phosphorylation that leads to clustering of acetylcholine receptors (AChRs) in the postsynaptic region of the skeletal muscle. Additionally, the ectodomain of LRP4 is necessary for differentiation...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Ohkawara, Bisei, Kobayakawa, Akinori, Kanbara, Shunsuke, Hattori, Takako, Kubota, Satoshi, Ito, Mikako, Masuda, Akio, Takigawa, Masaharu, Lyons, Karen M, Ishiguro, Naoki, Ohno, Kinji
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403661/
https://ncbi.nlm.nih.gov/pubmed/32558157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201948462
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