Verapamil Protects against Cartilage Degradation in Osteoarthritis by Inhibiting Wnt/β-Catenin Signaling

In past years, the canonical Wnt/β-catenin signaling pathway has emerged as a critical regulator of cartilage development and homeostasis. FRZB, a soluble antagonist of Wnt signaling, has been studied in osteoarthritis (OA) animal models and OA patients as a modulator of Wnt signaling. We screened f...

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Hlavní autoři: Takamatsu, Akira, Ohkawara, Bisei, Ito, Mikako, Masuda, Akio, Sakai, Tadahiro, Ishiguro, Naoki, Ohno, Kinji
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962439/
https://ncbi.nlm.nih.gov/pubmed/24658359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092699
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