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Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug-Resistant Cells
BACKGROUND: LCL161, a SMAC’S small molecule mimetic, can bind to a variety of IAPs and activate Caspases. We found that on its own, LCL161induces apoptosis of drug-resistant breast cancer cells by binding to a variety of IAPs and activating Caspases. However, when LCL161 is used in combination with...
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| Udgivet i: | Anticancer Agents Med Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Bentham Science Publishers
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7403652/ https://ncbi.nlm.nih.gov/pubmed/32053082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1871520620666200213102849 |
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