Treatment of mice with S4B6 IL-2 complex prevents lethal toxoplasmosis via IL-12- and IL-18-dependent interferon-gamma production by non-CD4 immune cells

Toxoplasmic encephalitis is an AIDS-defining condition. The decline of IFN-γ-producing CD4(+) T cells in AIDS is a major contributing factor in reactivation of quiescent Toxoplasma gondii to an actively replicating stage of infection. Hence, it is important to characterize CD4-independent mechanisms...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kupz, Andreas, Pai, Saparna, Giacomin, Paul R., Whan, Jennifer A., Walker, Robert A., Hammoudi, Pierre-Mehdi, Smith, Nicholas C., Miller, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403597/
https://ncbi.nlm.nih.gov/pubmed/32753607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70102-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados