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Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis

During viral infection, the host cell synthesizes high amounts of viral proteins, which often causes stress to the endoplasmic reticulum (ER). To manage abnormal ER stress, mammalian cells trigger a response called the unfolded protein response (UPR). Previous studies have indicated that porcine rep...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Chen, Quangang, Men, Yanjuan, Wang, Dang, Xu, Deqin, Liu, Suyan, Xiao, Shaobo, Fang, Liurong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403369/
https://ncbi.nlm.nih.gov/pubmed/32753633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69959-z
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