Porcine reproductive and respiratory syndrome virus infection induces endoplasmic reticulum stress, facilitates virus replication, and contributes to autophagy and apoptosis

During viral infection, the host cell synthesizes high amounts of viral proteins, which often causes stress to the endoplasmic reticulum (ER). To manage abnormal ER stress, mammalian cells trigger a response called the unfolded protein response (UPR). Previous studies have indicated that porcine rep...

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Publicado en:Sci Rep
Main Authors: Chen, Quangang, Men, Yanjuan, Wang, Dang, Xu, Deqin, Liu, Suyan, Xiao, Shaobo, Fang, Liurong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7403369/
https://ncbi.nlm.nih.gov/pubmed/32753633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69959-z
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