Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Coronavirus disease 2019 (COVID-19) is currently a global pandemic, but human immune responses to the virus remain poorly understood. We used high-dimensional cytometry to analyze 125 COVID-19 patients and compare them with recovered and healthy individuals. Integrated analysis of ~200 immune and ~5...

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Gepubliceerd in:Science
Hoofdauteurs: Mathew, Divij, Giles, Josephine R., Baxter, Amy E., Oldridge, Derek A., Greenplate, Allison R., Wu, Jennifer E., Alanio, Cécile, Kuri-Cervantes, Leticia, Pampena, M. Betina, D’Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P., Weisman, Ariel R., Ittner, Caroline A. G., Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C., Anderson, Elizabeth M., Weirick, Madison E., Gouma, Sigrid, Arevalo, Claudia P., Bolton, Marcus J., Chen, Fang, Lacey, Simon F., Ramage, Holly, Cherry, Sara, Hensley, Scott E., Apostolidis, Sokratis A., Huang, Alexander C., Vella, Laura A., Betts, Michael R., Meyer, Nuala J., Wherry, E. John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2020
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402624/
https://ncbi.nlm.nih.gov/pubmed/32669297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc8511
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