Experimental Renovascular Disease Induces Endothelial Cell Mitochondrial Damage and Impairs Endothelium-Dependent Relaxation of Renal Artery Segments

BACKGROUND: Mitochondria modulate endothelial cell (EC) function, but may be damaged during renal disease. We hypothesized that the ischemic and metabolic constituents of swine renovascular disease (RVD) induce mitochondrial damage and impair the function of renal artery ECs. METHODS: Pigs were stud...

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Detalhes bibliográficos
Publicado no:Am J Hypertens
Main Authors: Nargesi, Arash Aghajani, Zhu, Xiang-Yang, Saadiq, Ishran M, Jordan, Kyra L, Lerman, Amir, Lerman, Lilach O, Eirin, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Original Contributions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402225/
https://ncbi.nlm.nih.gov/pubmed/32179886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpaa047
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