Experimental Renovascular Disease Induces Endothelial Cell Mitochondrial Damage and Impairs Endothelium-Dependent Relaxation of Renal Artery Segments

BACKGROUND: Mitochondria modulate endothelial cell (EC) function, but may be damaged during renal disease. We hypothesized that the ischemic and metabolic constituents of swine renovascular disease (RVD) induce mitochondrial damage and impair the function of renal artery ECs. METHODS: Pigs were stud...

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Détails bibliographiques
Publié dans:Am J Hypertens
Auteurs principaux: Nargesi, Arash Aghajani, Zhu, Xiang-Yang, Saadiq, Ishran M, Jordan, Kyra L, Lerman, Amir, Lerman, Lilach O, Eirin, Alfonso
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Original Contributions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7402225/
https://ncbi.nlm.nih.gov/pubmed/32179886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpaa047
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