Complement Activation Levels Are Related to Disease Stage in AMD

PURPOSE: To study the levels of complement activation in different disease stages of AMD and the influence of genetic polymorphisms in complement genes. METHODS: We included 797 patients with AMD and 945 controls from the European Genetic Database. Patients were grouped into five AMD stages: early A...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Heesterbeek, Thomas J., Lechanteur, Yara T. E., Lorés-Motta, Laura, Schick, Tina, Daha, Mohamed R., Altay, Lebriz, Liakopoulos, Sandra, Smailhodzic, Dzenita, den Hollander, Anneke I., Hoyng, Carel B., de Jong, Eiko K., Klevering, B. Jeroen
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2020
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Retina
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401663/
https://ncbi.nlm.nih.gov/pubmed/32176267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.3.18
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