62. PRESENCE OF EXTRACRANIAL TUMORS INFLUENCES RESPONSE TO IMMUNE CHECKPOINT INHIBITORS IN A PRE-CLINICAL MODEL OF MELANOMA BRAIN METASTASIS

Up to 75% of patients with melanoma develop brain metastases. While immune checkpoint inhibitors (ICI) targeting PD-1 and CTLA4 have revolutionized the treatment of metastatic melanoma, responses within the immune-specialized microenvironment of the brain are not well understood and there is a pauci...

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Vydáno v:Neurooncol Adv
Hlavní autoři: Nayyar, Naema, Singh, Mohini, Stocking, Jackson, Brehm, Michael, Brastianos, Priscilla
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
Supplement Abstracts
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401395/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa073.050
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