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MicroRNA-148a-3p inhibits progression of hepatocelluar carcimoma by repressing SMAD2 expression in an Ago2 dependent manner

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most prevalent common cancer worldwide with high mortality. Transforming growth factor-β (TGF-β) signaling pathway was reported dysregulated during liver cancer formation and progression. As a key component of TGF-β signaling, the role of SMAD...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Huang, Zhao, Wen, Jingyuan, Yu, Jingjing, Liao, Jingyu, Liu, Sha, Cai, Ning, Liang, Huifang, Chen, Xiaoping, Ding, Zeyang, Zhang, Bixiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401232/
https://ncbi.nlm.nih.gov/pubmed/32746934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01649-0
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