Unregulated Sphingolipid Biosynthesis in Gene-Edited Arabidopsis ORM Mutants Results in Nonviable Seeds with Strongly Reduced Oil Content

Orosomucoid-like proteins (ORMs) interact with serine palmitoyltransferase (SPT) to negatively regulate sphingolipid biosynthesis, a reversible process critical for balancing the intracellular sphingolipid levels needed for growth and programmed cell death. Here, we show that ORM1 and ORM2 are essen...

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Pubblicato in:Plant Cell
Autori principali: Gonzalez-Solis, Ariadna, Han, Gongshe, Gan, Lu, Li, Yunfeng, Markham, Jonathan E., Cahoon, Rebecca E., Dunn, Teresa M., Cahoon, Edgar B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Plant Biologists 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7401009/
https://ncbi.nlm.nih.gov/pubmed/32527862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.20.00015
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