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Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1

Sphingolipid (SL) biosynthesis is negatively regulated by the highly conserved endoplasmic reticulum-localized Orm family proteins. Defective SL synthesis in Saccharomyces cerevisiae leads to increased phosphorylation and inhibition of Orm proteins by the kinase Ypk1. Here we present evidence that t...

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Vydáno v:J Biol Chem
Hlavní autoři: Chauhan, Neha, Han, Gongshe, Somashekarappa, Niranjanakumari, Gable, Kenneth, Dunn, Teresa, Kohlwein, Sepp D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732232/
https://ncbi.nlm.nih.gov/pubmed/26634277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693200
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