GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes

The mechanisms mediating suppression of reproduction in response to decreased nutrient availability remain undefined, with studies suggesting regulation occurs within the hypothalamus, pituitary, or gonads. By manipulating glucose utilization and GLUT1 expression in a pituitary gonadotrope cell mode...

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Vydáno v:Sci Rep
Hlavní autoři: Nicholas, Dequina A., Knight, Vashti S., Tonsfeldt, Karen J., Terasaka, Tomohiro, Molinar-Inglis, Olivia, Stephens, Shannon B. Z., Trejo, JoAnn, Kauffman, Alexander S., Mellon, Pamela L., Lawson, Mark A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400764/
https://ncbi.nlm.nih.gov/pubmed/32747664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69913-z
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