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End-binding E3 ubiquitin ligases enable protease signaling
Post-translational modifications (PTMs) direct the assembly of protein complexes. In this context, proteolysis is a unique PTM because it is irreversible; the hydrolysis of the peptide backbone generates separate fragments bearing a new N and C terminus. Proteolysis can “re-wire” protein-protein int...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7400744/ https://ncbi.nlm.nih.gov/pubmed/31714737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00621 |
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