ADAMDEC1 maintains a growth factor signaling loop in cancer stem cells

Glioblastomas (GBM) are lethal brain tumors where poor outcome is attributed to cellular heterogeneity, therapeutic resistance, and a highly infiltrative nature. These characteristics are preferentially linked to GBM cancer stem cells (GSCs), but how GSCs maintain their stemness is incompletely unde...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Jimenez-Pascual, Ana, Hale, James S., Kordowski, Anja, Pugh, Jamie, Silver, Daniel J., Bayik, Defne, Roversi, Gustavo, Alban, Tyler J., Rao, Shilpa, Chen, Rui, McIntyre, Thomas M., Colombo, Giorgio, Taraboletti, Giulia, Holmberg, Karl O., Forsberg-Nilsson, Karin, Lathia, Justin D., Siebzehnrubl, Florian A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400732/
https://ncbi.nlm.nih.gov/pubmed/31434712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-18-1308
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