The metalloproteinase ADAMDEC1 maintains a novel growth factor signalling loop in glioblastoma cancer stem cells

Glioblastomas (GBM) are lethal brain tumours where poor outcome is attributed to cellular heterogeneity, therapeutic resistance, and a highly infiltrative nature. These characteristics are preferentially linked to GBM cancer stem cells (GSCs), but how GSCs maintain their stemness is incompletely und...

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Publicado no:Neuro Oncol
Main Authors: Jimenez-Pascual, Ana, Hale, James, Kordowski, Anja, Pugh, Jamie, Rao, Shilpa, Silver, Daniel, Alban, Tyler, Watson, Defne, Chen, Rui, McIntyre, Thomas, Colombo, Giorgio, Taraboletti, Giulia, Holmberg, Karl, Forsberg-Nilsson, Karin, Lathia, Justin, Siebzehnrubl, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6789953/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz167.003
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