Small cell transformation of ROS1 fusion-positive lung cancer resistant to ROS1 inhibition

Histologic transformation from non-small cell to small cell lung cancer has been reported as a resistance mechanism to targeted therapy in EGFR-mutant and ALK fusion-positive lung cancers. Whether small cell transformation occurs in other oncogene-driven lung cancers remains unknown. Here we analyze...

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發表在:NPJ Precis Oncol
Main Authors: Lin, Jessica J., Langenbucher, Adam, Gupta, Pranav, Yoda, Satoshi, Fetter, Isobel J., Rooney, Marguerite, Do, Andrew, Kem, Marina, Chang, Kylie Prutisto, Oh, Audris Y., Chin, Emily, Juric, Dejan, Corcoran, Ryan B., Dagogo-Jack, Ibiayi, Gainor, Justin F., Stone, James R., Lennerz, Jochen K., Lawrence, Michael S., Hata, Aaron N., Mino-Kenudson, Mari, Shaw, Alice T.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
Case Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400592/
https://ncbi.nlm.nih.gov/pubmed/32802958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-0127-9
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