Small cell transformation of ROS1 fusion-positive lung cancer resistant to ROS1 inhibition

Histologic transformation from non-small cell to small cell lung cancer has been reported as a resistance mechanism to targeted therapy in EGFR-mutant and ALK fusion-positive lung cancers. Whether small cell transformation occurs in other oncogene-driven lung cancers remains unknown. Here we analyze...

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Detalhes bibliográficos
Publicado no:NPJ Precis Oncol
Main Authors: Lin, Jessica J., Langenbucher, Adam, Gupta, Pranav, Yoda, Satoshi, Fetter, Isobel J., Rooney, Marguerite, Do, Andrew, Kem, Marina, Chang, Kylie Prutisto, Oh, Audris Y., Chin, Emily, Juric, Dejan, Corcoran, Ryan B., Dagogo-Jack, Ibiayi, Gainor, Justin F., Stone, James R., Lennerz, Jochen K., Lawrence, Michael S., Hata, Aaron N., Mino-Kenudson, Mari, Shaw, Alice T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400592/
https://ncbi.nlm.nih.gov/pubmed/32802958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-0127-9
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