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Human pluripotent stem cell-derived cardiomyocytes as a target platform for paracrine protection by cardiac mesenchymal stromal cells

Ischemic heart disease remains the foremost cause of death globally, with survivors at risk for subsequent heart failure. Paradoxically, cell therapies to offset cardiomyocyte loss after ischemic injury improve long-term cardiac function despite a lack of durable engraftment. An evolving consensus,...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Constantinou, Chrystalla, Miranda, Antonio M. A., Chaves, Patricia, Bellahcene, Mohamed, Massaia, Andrea, Cheng, Kevin, Samari, Sara, Rothery, Stephen M., Chandler, Anita M., Schwarz, Richard P., Harding, Sian E., Punjabi, Prakash, Schneider, Michael D., Noseda, Michela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7400574/
https://ncbi.nlm.nih.gov/pubmed/32747668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69495-w
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