Intrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45(low)CD271(+) Multipotential Stromal Cells (BM-MSCs): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation

Skeletal aging is associated with reduced proliferative potential of bone marrow (BM) multipotential stromal cells (MSCs). Recent data suggest the involvement of type 1 interferon (IFN1) signalling in hematopoietic stem cell (HSC) senescence. Considering that BM-HSCs and BM-MSCs share the same BM ni...

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Detaylı Bibliyografya
Yayımlandı:Biomedicines
Asıl Yazarlar: Ganguly, Payal, Burska, Agata N., Davis, Charlotte L.M., El-Jawhari, Jehan J., Giannoudis, Peter V., Jones, Elena A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399891/
https://ncbi.nlm.nih.gov/pubmed/32679782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8070214
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