The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45(low)CD271(+) Phenotype

Uncultured mesenchymal stromal cells (MSCs) are increasingly used in therapies; however, the effects of donor age on their biological characteristics and gene expression remain unclear. The aim of this study was to investigate age-related changes in bone marrow (BM) MSCs following minimal or no cult...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Ganguly, Payal, El-Jawhari, Jehan J., Burska, Agata N., Ponchel, Frederique, Giannoudis, Peter V., Jones, Elena A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6701348/
https://ncbi.nlm.nih.gov/pubmed/31467563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5197983
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