MiR-181c-5p Promotes Inflammatory Response during Hypoxia/Reoxygenation Injury by Downregulating Protein Tyrosine Phosphatase Nonreceptor Type 4 in H9C2 Cardiomyocytes

BACKGROUND: Constitutive nuclear factor kappa B (NFκB) activation has been shown to exacerbate during myocardial ischemia/reperfusion (I/R) injury. We recently showed that miR-181c-5p exacerbated cardiomyocytes injury and apoptosis by directly targeting the 3′-untranslated region of protein tyrosine...

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Publicado en:Oxid Med Cell Longev
Autores principales: Wang, Sheng, Ge, Liang, Zhang, Dengwen, Wang, Lin, Liu, Hao, Ye, Xiaodong, Liang, Wanling, Li, Jun, Ma, Haichun, Cai, Yin, Xia, Zhengyuan
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399766/
https://ncbi.nlm.nih.gov/pubmed/32774684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7913418
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