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Raising Placebo Efficacy in Antidepressant Trials Across Decades Explained by Small-Study Effects: A Meta-Reanalysis

BACKGROUND: Recent meta-analyses reported placebo response rate in antidepressant trials to be stable since the 1970s. These meta-analyses however were limited in considering only linear time trends, assessed trial-level covariates based on single-model hypothesis testing only, and did not adjust fo...

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Detalhes bibliográficos
Publicado no:Front Psychiatry
Autor principal: Holper, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399231/
https://ncbi.nlm.nih.gov/pubmed/32848900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2020.00633
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