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Drosophila Skp1 Homologue SkpA Plays a Neuroprotective Role in Adult Brain

Skp1, a component of the ubiquitin E3 ligases, was found to be decreased in the brains of sporadic Parkinson's disease (PD) patients, and its overexpression prevented death of murine neurons in culture. Here we expose the neuroprotective role of the Drosophila skp1 homolog, skpA, in the adult b...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Dabool, Lital, Hakim-Mishnaevski, Ketty, Juravlev, Liza, Flint-Brodsly, Naama, Mandel, Silvia, Kurant, Estee
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399183/
https://ncbi.nlm.nih.gov/pubmed/32739834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101375
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