Drosophila Skp1 Homologue SkpA Plays a Neuroprotective Role in Adult Brain

Skp1, a component of the ubiquitin E3 ligases, was found to be decreased in the brains of sporadic Parkinson's disease (PD) patients, and its overexpression prevented death of murine neurons in culture. Here we expose the neuroprotective role of the Drosophila skp1 homolog, skpA, in the adult b...

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Udgivet i:iScience
Main Authors: Dabool, Lital, Hakim-Mishnaevski, Ketty, Juravlev, Liza, Flint-Brodsly, Naama, Mandel, Silvia, Kurant, Estee
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399183/
https://ncbi.nlm.nih.gov/pubmed/32739834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101375
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