TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients

Background: Head and neck squamous cell carcinoma (HNSCC) is usually associated to tobacco and alcohol consumption. Increased telomerase activity has been consistently detected in 80–90% of malignant tumors, including HNSCC. Mutations within the promoter region of telomerase reverse transcriptase (T...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Arantes, Lidia Maria Rebolho Batista, Cruvinel-Carloni, Adriana, de Carvalho, Ana Carolina, Sorroche, Bruna Pereira, Carvalho, André Lopes, Scapulatempo-Neto, Cristovam, Reis, Rui Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399085/
https://ncbi.nlm.nih.gov/pubmed/32850388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01275
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