TERT Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients

Background: Head and neck squamous cell carcinoma (HNSCC) is usually associated to tobacco and alcohol consumption. Increased telomerase activity has been consistently detected in 80–90% of malignant tumors, including HNSCC. Mutations within the promoter region of telomerase reverse transcriptase (T...

Full description

Saved in:
Bibliographic Details
Published in:Front Oncol
Main Authors: Arantes, Lidia Maria Rebolho Batista, Cruvinel-Carloni, Adriana, de Carvalho, Ana Carolina, Sorroche, Bruna Pereira, Carvalho, André Lopes, Scapulatempo-Neto, Cristovam, Reis, Rui Manuel
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7399085/
https://ncbi.nlm.nih.gov/pubmed/32850388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01275
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items