Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Relapses in multiple sclerosis can result in irreversible nervous system tissue injury. If these events could be detected early, targeted immunotherapy could potentially slow disease progression. We describe the use of engineered biomaterial-based immunological niches amenable to biopsy to provide i...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Morris, Aaron H., Hughes, Kevin R., Oakes, Robert S., Cai, Michelle M., Miller, Stephen D., Irani, David N., Shea, Lonnie D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398910/
https://ncbi.nlm.nih.gov/pubmed/32747712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17629-z
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