Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Relapses in multiple sclerosis can result in irreversible nervous system tissue injury. If these events could be detected early, targeted immunotherapy could potentially slow disease progression. We describe the use of engineered biomaterial-based immunological niches amenable to biopsy to provide i...

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Udgivet i:Nat Commun
Main Authors: Morris, Aaron H., Hughes, Kevin R., Oakes, Robert S., Cai, Michelle M., Miller, Stephen D., Irani, David N., Shea, Lonnie D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398910/
https://ncbi.nlm.nih.gov/pubmed/32747712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17629-z
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