MiTF is Associated with Chemoresistance to Cisplatin in A549 Lung Cancer Cells via Modulating Lysosomal Biogenesis and Autophagy

BACKGROUND: Non-small cell lung carcinoma (NSCLC) is often fatal; advanced NSCLC has a 5-year survival rate less than 20%. Platinum-based chemotherapy, in particular, cis-diamminedichloroplatinum (II) (cisplatin or DDP), is employed for the treatment of NSCLC; however, the drug resistance occurs fre...

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Detalhes bibliográficos
Publicado no:Cancer Manag Res
Main Authors: Li, Wei, Qin, Xia, Wang, Bin, Xu, Ge, Zhang, Jun, Jiang, Xuejun, Chen, Chengzhi, Qiu, Feng, Zou, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398682/
https://ncbi.nlm.nih.gov/pubmed/32801894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S255939
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