Effective inhibition of cancer cells by recombinant adenovirus expressing EGFR-targeting artificial microRNA and reversed-caspase-3

The EGFR-targeting cancer therapies are commonly facing drug resistance, mostly due to mutations. Gene therapy with artificial microRNA targeting EGFR conserved sequence may avoid such problem. In this study, we constructed a recombinant adenovirus expressing EGFR-targeting artificial microRNA and a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Yan, Maoxiao, Chen, Jia, Jiang, Hua, Xie, Yuqiong, Li, Chunchun, Chen, Lihong, Yang, Beibei, Cao, Jiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398494/
https://ncbi.nlm.nih.gov/pubmed/32745124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0237098
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