Pharmacogenetic interactions between antiretroviral drugs and vaginally-administered hormonal contraceptives

OBJECTIVE: In AIDS Clinical Trials Group study A5316, efavirenz significantly lowered plasma concentrations of etonogestrel and ethinyl estradiol, given as a vaginal ring, while atazanavir/ritonavir increased etonogestrel and lowered ethinyl estradiol concentrations. We characterized the pharmacogen...

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Publié dans:Pharmacogenet Genomics
Auteurs principaux: Haas, David W., Cramer, Yoninah S., Godfrey, Catherine, Rosenkranz, Susan L., Aweeka, Francesca, Berzins, Baiba, Coombs, Robert, Coughlin, Kristine, Moran, Laura E., Gingrich, David, Zorrilla, Carmen D., Baker, Paxton, Cohn, Susan E., Scarsi, Kimberly K.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398416/
https://ncbi.nlm.nih.gov/pubmed/32106141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000396
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