Pharmacogenetic interactions between antiretroviral drugs and vaginally-administered hormonal contraceptives

OBJECTIVE: In AIDS Clinical Trials Group study A5316, efavirenz significantly lowered plasma concentrations of etonogestrel and ethinyl estradiol, given as a vaginal ring, while atazanavir/ritonavir increased etonogestrel and lowered ethinyl estradiol concentrations. We characterized the pharmacogen...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Haas, David W., Cramer, Yoninah S., Godfrey, Catherine, Rosenkranz, Susan L., Aweeka, Francesca, Berzins, Baiba, Coombs, Robert, Coughlin, Kristine, Moran, Laura E., Gingrich, David, Zorrilla, Carmen D., Baker, Paxton, Cohn, Susan E., Scarsi, Kimberly K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398416/
https://ncbi.nlm.nih.gov/pubmed/32106141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000396
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