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Mechanosensing through YAP controls T cell activation and metabolism
Upon immunogenic challenge, lymph nodes become mechanically stiff as immune cells activate and proliferate within their encapsulated environments, and with resolution, they reestablish a soft baseline state. Here we show that sensing these mechanical changes in the microenvironment requires the mech...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398163/ https://ncbi.nlm.nih.gov/pubmed/32484502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200053 |
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